Our latest collaboration with the Chien lab is in Nature Biomedical Engineering!
February 2024: Marco L. represents the Brinks Lab at BPS24
Marco will fly all the way to Philadelphia to participate to the Biophysical Society annual meeting and represent the lab there. Exciting!
February 2024: our preprint about plasmonic enhancement of GEVIs is on bioRxiv!
We are very excited to announce that the work of Marco L., Qiangrui, Xin and many other collaborators is now avaliable as a preprint on bioRxiv! Give it a read and let us know if you have feedback about it!
January 2024: Mike Lindhout joins us as a technician
Mike will help us with wetlab and cell work, welcome!
October 2023: Marco L. starts as a biophysics lecturer at Utrecht University
Congratulations Marco for starting a new, exciting position in higher education! Marco will finish his PhD contract part-time, and start teaching light microscopy and biophysics in the Molecular and Biophysical Life Sciences Bachelor's of Utrecht University. Good luck!
October 2023: Selina moves on to a new position in Erasmus MC, Rotterdam
Selina will start as a research analyst in the Department of Clinical Genetics, Erasmus MC. Good luck Selina and thank you for your work with us!
September 2023: Elif finishes her internship
Thanks Elif for your contribution and good luck with your studies!
August 2023: Xin starts a new position at Nearfield Instruments!
Xin has finished his work as PhD candidate and moves on in his career as a signal and image processing engineer at Nearfield Instruments. We thank Xin for his invaluable contribution, congratulate him for the new position and wish good luck for his future endeavors!
July 2023: Lars finishes his MSc thesis
Thank you Lars for your contribution to the lab, and good luck with your future PhD!
June 2023: Elif Yilmaz joins us for an intership
We welcome Elif from Bilkent University (Ankara, Turkey) as a summer intern. Thanks to the Erasmus+ traineeship programme, she will help us for three months by comparing the analytical model just published with FDTD simulations.
July 2023: Marco's theoretical review of plasmonic resonance is published in the American Journal of Physics!
Not really a literature review, but more of an educational tutorial, Marco Locarno's first paper explores all the steps that lead to an explanation of the plasmonic resonances through the development of a comprehensive analytical model. Learn more about it here.
May 2023: Xin's literature review is published on ACS Physical Chemistry Au
Check out the (open access) work of Xin, Vidya, Lars and Marco about the photocycle of proton-pumping rhodopsins in our new ACS Physical Chemistry Au publication!
April 2023: Vidya and Xin's article about Heliorhodopsin as a GEVI is published on the Journal of Biological Chemistry
How does a microbial rhodopsin become a voltage indicator? Discover it in the article by Vidya and Xin, made possible thanks to the work of our students Delizzia and Mels!
April 5th 2023: Marco L. wins the fifth poster award for his work on plasmonic enhancement!
Marco Locarno wins his fifth poster award at NWO Physics, in the category "Science Communication". What an intense journey has been!
To rest, Astra will now retire, but don't you worry. You can still read her story on the poster in the corridor next to F060 (Building 22, TU Delft) or online at the (not so) secret page on this website.
To rest, Astra will now retire, but don't you worry. You can still read her story on the poster in the corridor next to F060 (Building 22, TU Delft) or online at the (not so) secret page on this website.
November 28 2022: Daan is promoted to Associate Professor
The university in all their inscrutability decided to want to keep us around for a while longer, gave Daan tenure and promoted him to associate professor! Thanks to everyone in the lab whose hard work, perseverance, intelligence and creativity made this possible!
October 6th 2022: we won the Digital Transformations 2022 Computable award!Our work with Miao-Ping Chien (Erasmus MC) just won the Digital Transformations 2022 Computable award!
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September 29th 2022: Convergence Health and Technology Flagship "Integrative Neuromedicine" is awarded!
Daan leads a consortium that has been awarded a Convergence flagship! (and is a member of two other flagships out of the ten awarded!) These flagships will strengthen our collaborations in the field of Integrative Neuromedicine, Innovative Imaging and cellular heterogeneteity!
April 1st 2022: Xin's paper is in Journal of Optics!
We popped champagne and had some ice cream: Xin's paper on the Octoscope is out!
Thanks to the hard work of Xin, Lex, Teun, Greta, Ruud, Izak and Vidya, we can finally present you the Octoscope: a versatile, multimodal device for all-optical electrophysiology. This is what we work with daily, so make sure you'll read the paper!
Congratulations!
Thanks to the hard work of Xin, Lex, Teun, Greta, Ruud, Izak and Vidya, we can finally present you the Octoscope: a versatile, multimodal device for all-optical electrophysiology. This is what we work with daily, so make sure you'll read the paper!
Congratulations!
March 17th 2022: the paper by Li, Pin-Rui and Max on linking genotypes and phenotypes of cancer cells is in Nature Biomedical Engineering!
Our collaboration with Miao-Ping Chien's lab is as fruitful as ever: check out the latest paper to discover how real-time optical tagging and image analysis can help study cancer cells!
We are also in the news:
We are also in the news:
March 2022: Our scientific family gets bigger and spreads around the world too!
We say goodbye to Vidya and Thijs, thank them for their contributions and wish them good luck for their future careers! Vidya will keep collaborating with us from the sunny San Diego, where during her postdoc she will investigate neurodevelopment in organoids; Thijs will carry out his internship before concluding his MSc degree in Nanobiology.
At the same time, we're happy to tell you that the lab is growing too! We welcome all the new students who will contribute to our research:
At the same time, we're happy to tell you that the lab is growing too! We welcome all the new students who will contribute to our research:
- Rui Silva will carry out his PhD in collaboration with Gao's lab in Erasmus MC, in Rotterdam. His project will involve in vivo voltage imaging.
- Marco Post will do his internship with us, focusing on on directed evolution of proteins under two-photon imaging conditions.
- Matteo Pirro joins us for a joint MSc thesis under the supervision of Clémentine Boutry, from the Department of Microelectronics (TU Delft). He will work on the mechanical stimulation of neural cells with voltage microscopy imaging, towards soft biodegradable implants.
- Robin Liu and Thijn Hoekstra join from the Nanobiology programme for their BEPs, respectively on analysis of FLIM data and computational modeling of neural networks.
- Finally, Polina Kostina returns after her internship to carry out her Nanobiology BEP with us, focusing on machine learning for recognition of neural progenitor cells (NPCs).
December 7th 2021: William's paper on linearly polarized GEVI excitation is in Biophysical Journal!
The devil is in the details: detailed control and detailed observation of the the excitation light provides new detailed information about GEVIs!
October 26th 2021: BIOlab sees the light!
Together with our Colleagues Elizabeth Carroll, Kristin Grußmayer, Zoltan Perko, Nergis Tömen and Wendelin Böhmer, we wrote an application to become a Delft Artificial Intelligence lab, which was granted! As of today the Biomedical Intervention Optimization lab (BIOlab) is a fact! We will develop AI methodology for efficient decision making in and interaction with biological and biomedical measurements: examples include optogenetic interventions and optimized radiotherapy!
Update: we have positions available on reinforcement learning and efficient AI in neuroscience, and AI in cancer treatment and superresolution microscopy!
Update: we have positions available on reinforcement learning and efficient AI in neuroscience, and AI in cancer treatment and superresolution microscopy!
October 13th 2021: the FUNseq paper is on BioRxiv
Exciting work with the Chien lab on functional single cell sequencing, heralding a new way to diagnose and investigate cancer!
October 11th 2021: Cryo-TIRF in Optics Express
Vidya helped the lab of Bernd Rieger obtain cellular data on a new Cryo-TIRF microscope. Congratulations!
August 1st 2021: Convergence open mind grant: e-FUNseq awarded
Together with the lab of Miao-Ping Chien we got a grant to integrate voltage imaging with functional single cell sequencing!
May 5th 2021: NovArch is published in Science Advances!
Our paper on how to increase the SNR of voltage imaging in tissue via a targeted photoactivation scheme, making dendritic voltage imaging possible, is published in Science Advances! THanks to everyone who contributed!
December 1st 2019: The lab is awarded an NWO-XS grant
We have been awarded a grant in NWO's new XS scheme, where high-risk high-reward ideas are judged by other grant applicants. Thanks, fellow scientists!
September 3rd 2019: We have been awarded an ERC Starting Grant!Thanks to the hard work of our excellent students, PhDs and Postdocs, the lab has been awarded an ERC starting grant! we are very grateful to the European research council and excited for the opportunity this represents. Here is a TU Delft Press release, and a more in depth description on the applied sciences website.
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May 1st 2019: PaQuasar3 in Nature!
Yoav's paper 'Voltage Imaging and Optogenetics reveal behavior-dependent changes in hippocampal dynamics' is online in Nature! Congratulations on a fantastic piece of work, Yoav! Read the paper here. Read the Harvard Press release here.
October 2018: Daan accepts a position as group leader at Erasmus MC!
The Brinks lab is spreading! Daan has accepted a second position as group leader in the Department of Molecular Genetics at Erasmus MC. Our lab now exists in two places at once! Thanks to Roland Kanaar, head of the molecular genetics department, for taking chance on us! We're looking forward to contributing to the molecular genetics research, collaborating with new colleagues on exciting biomedical and clinical projects, welcoming Erasmus MC students to our lab, and most of all combining the strengths of Delft and Erasmus to do awesome science!
September 19 2018: paQuasAr and NovArch in Nature News.
Check out this Nature News feature describing the advent of Voltage Imaging with Genetically Encoded Voltage Indicators and highlighting the recent advances in deep tissue voltage imaging, in particular our work on PaQuasar and Novarch!
July 17 2018:
The Brinks lab is awarded a NWO START UP grant!
We'll use this for nanoscopic investigation of electrical dynamics in neurons.
Thanks to everyone in the lab who has worked so hard on our preliminary data!
link to announcement Thanks NWO!
Thanks to everyone in the lab who has worked so hard on our preliminary data!
link to announcement Thanks NWO!